Taking Up Intractable Anal Diseases

Intractable and rare diseases research.

Intractable diseases, literally derived from the Japanese word 'nanbyo', mainly refer to rare diseases that have resulted mostly from unidentifiable causes and/or lack of clearly established or curable treatments. Currently, it is estimated that there are 5,000-7,000 distinct rare diseases worldwide, of which 80% have been identified as having genetic origins and 50% occuring in childhood and l...

Intractable and rare diseases research in Asia.

Intractable and rare diseases are an important public health issue and a challenge to medical care. In recent years, much progress has been made in the United States (US), the European Union (EU), and some parts of Asia including Japan, South Korea, and Taiwan, involving specific legislation to encourage discovery and development of orphan drugs, patients' advocacy organizations to provide vast...

Hopes for intractable and rare diseases research.

February 28, 2013 marks the sixth international "Rare Disease Day". On and around this day, hundreds of patient organizations from more than 60 countries and regions worldwide plan to host awareness campaigns in line with this year's theme, "Rare Disorders without Borders". Public awareness of intractable and rare diseases has heightened in recent decades. Much progress has also been made world...

ABC of colorectal diseases. Sexually transmitted diseases and anal papillomas.

ABC of colorectal diseases. Anal cancer.

Anal cancer is relatively uncommon, accounting for about 4% of anorectal malignancies. The condition is of increasing interest owing to appreciable changes in the patterns of treatment. The traditional treatment for anal cancer was a radical abdominoperineal excision, leaving the patient with a permanent colostomy. Emerging evidence shows that most anal cancers respond to a combination of radio...